Digestive Refresh Research Collection

Cascara Sagrada

https://www.ncbi.nlm.nih.gov/pubmed/17019678
https://www.ncbi.nlm.nih.gov/pubmed/17935676
https://www.spandidos-publications.com/ijo/46/4/1619
http://europepmc.org/abstract/med/16828249
https://www.ncbi.nlm.nih.gov/pubmed/18301953


Senna Leaf Powder
Chevallier A. Encyclopedia of Medicinal Plants . New York, NY: DK Publishing; 1996:72.


Robbers JE, Tyler VE, eds. Tyler's Herbs of Choice . Binghamton, NY: The Haworth Herbal Press; 1999:60-61.


Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-Care Professionals . London, England: The Pharmaceutical Press; 1996:243-244.

Bisset NG. Herbal Drugs and Phytopharmaceuticals . Stuttgart, Germany: Medpharm Scientific Publishers and Boca Raton, FL: CRC Press Inc; 1994;463-466.

Duke J. CRC Handbook of Medicinal Herbs . Boca Raton, FL: CRC Press Inc; 1985:102-103.

Heaton KW, Cripps HA. Straining at stool and laxative taking in an English population. Dig Dis Sci . 1993;38(6):1004-1008.

Vanderperren B, Rizzo M, Angenot L, Haufroid V, Jadoul M, Hantson P. Acute liver failure with renal impairment related to the abuse of senna anthraquinone glycosides. Ann Pharmacother . 2005;39(7-8):1353-1357.

Waltenberger B, Avula B, Ganzera M, Khan IA, Stuppner H, Khan SI. Transport of sennosides and sennidines from Cassia angustifolia and Cassia senna across Caco-2 monolayers—an in vitro model for intestinal absorption. Phytomedicine . 2008;15(5):373-377.

Ralevic V, Hoyle CH, Burnstock G. Effects of long-term laxative treatment on rat mesenteric resistance vessel responses in vitro. Gastroenterology . 1990;99(5):1352-1357.

Kiernan JA, Heinicke EA. Sennosides do not kill myenteric neurons in the colon of the rat or mouse. Neuroscience . 1989;30(3):837-842.


Fennel Seed Powder
http://lpi.oregonstate.edu/mic/health-disease/skin-health/vitamin-C
https://www.physiology.org/doi/abs/10.1152/ajpregu.00491.2005
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1753-4887.2001.tb07001.x
www.ncbi.nlm.nih.gov/pubmed/12868253
http://umm.edu/health/medical/altmed/condition/infantile-colic
https://www.sciencedirect.com/science/article/pii/S0944711312000815
http://jama.jamanetwork.com/article.aspx?articleid=412293

Bentonite Clay
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413170/
https://www.ncbi.nlm.nih.gov/pubmed/26831423
http://www.who.int/buruli/en/
https://www.ncbi.nlm.nih.gov/pubmed/26343723
https://www.ncbi.nlm.nih.gov/pubmed/8099348
https://www.ncbi.nlm.nih.gov/pubmed/9850994

Slippery Elm
http://www.ncbi.nlm.nih.gov/pubmed/23997718
https://www.ncbi.nlm.nih.gov/pubmed/20696007
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204705/
http://www.ncbi.nlm.nih.gov/pubmed/20954962
https://www.ncbi.nlm.nih.gov/pubmed/17212569


Aloe Ferox
http://www.aloeferox.us/faq
http://www.ncbi.nlm.nih.gov/pubmed/15043514
http://www.plantzafrica.com/plantab/aloeferox.htm
http://www.arkive.org/bitter-aloe/aloe-ferox/
http://www.traffic.org/species-reports/traffic_species_plants1.pdf
http://www.aloeplant.info/aloe-ferox-bitter-nutrient-rich-version-aloe-vera/
http://www.webmd.com/vitamins-supplements/ingredientmono-607-aloe.aspx?activeingredientid=607&activeingredientname=aloe

Cayenne Pepper Extract
https://www.ncbi.nlm.nih.gov/pubmed/12531428
http://www.ncbi.nlm.nih.gov/pubmed/16621751
http://www.ncbi.nlm.nih.gov/pubmed/12627807